![]() The clinicians are concerned due to increased evident of non-fermenters isolated from various respiratory specimens and also found associated with the diseases like pneumonia, cystic fibrosis and respiratory tract infections (RTI) especially in immunocompromised patients. This group includes diverse genera like Acinetobacter, Pseudomonas, Stenotrophomonas, Burkholderia, Flavobacterium, Chrysobacterium, Elizabethkingia, Weeksella, Spingobacterium, Moraxella, Psychrobacter, Neisseria, Bordetella, Ralstonia etc. 2Īpproximately 15% of isolates from clinical samples are NFGNB. Non-fermenting Gram negative bacilli (NFGNB) are assorted group of different aerobic, non-sporing bacilli that either incapable of utilizing glucose as a source of energy or utilizing it oxidatively rather than fermentatively. 1 So there is further need to evaluate RTI causative agents. The problem is much greater in developing countries. Etiological agents of RTI vary geographically and timely. 1 RTI are often misdiagnosed, mistreated and underestimated due to its nonspecific presentation. Respiratory tract infections (RTI) are among most‑common infectious diseases affecting population worldwide causing significant morbidity and mortality for all age groups. The most effective antibiotics were Tigecycline and Polymyxin B/ Colistin, however majority of them showed multidrug resistance. While other NFGNB like Elizabethkingia, Stenotrophomonas, Sphingomonas, Burkholderia and Chrysobacterium were isolated in few respiratory samples. Acinetobacter calcoacetecus baumanii complex 67(46.8%) was the commonest isolate followed by Psuedomonas aeruginosa 56(39.1%). Results and Conclusion: Patients mostly belonged to age group of 65 to 80 years and were 96(67%)male. Out of which NFGNB(391 samples), a total of 143 (36.57%) were from various respiratory samples were included in this study and were isolated on MacConkey and blood agar plates incubated at 35☌ for 24-48 hours. Our study also line up the singnificant role of NFGNB as respiratory pathogens.ģ91 (14.6 %) non-fermenters were isolated from 2678 clinical specimens. Material and Methods: The study was undertaken to identify various non- fermenters by additional conventional tests, isolated from patients having respiratory tract infection in department of Microbiology, SVPPGIP and SCBMCH Medical college, a Tertiary Care Center, Odisha. The NFGNB are a group of several different aerobic, non-sporing, Gram negative bacilli that either unable to utilize carbohydrates as a source of energy or withhold them through metabolic pathways other than the fermentation. The non-fermentative Gram negative bacilli (NFGNB) are often associated with RTI. ![]() So it is important to evaluate more for RTI causative agents. The risk factors of RTI vary geographically and timely(1). They are often misdiagnosed due to its nonspecific presentation in clinical settings. Introduction: Respiratory tract infections are the most common diseases that are associated with mortality and morbidity. ![]()
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